New quinoxalin-1,3,4-oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies.

Mirzazadeh, Roghieh; Asgari, Mohammad S; Barzegari, Ebrahim; Pedrood, Keyvan; Mohammadi-Khanaposhtani, Maryam; Sherafati, Maedeh; Larijani, Bagher; Rastegar, Hossein; Rahmani, Hojjat; Mahdavi, Mohammad; Taslimi, Parham; Üç, Eda M; Gulçin, Ilhami

Mirzazadeh, Roghieh; Asgari, Mohammad S; Barzegari, Ebrahim; Pedrood, Keyvan; Mohammadi-Khanaposhtani, Maryam; Sherafati, Maedeh; Larijani, Bagher; Rastegar, Hossein; Rahmani, Hojjat; Mahdavi, Mohammad; Taslimi, Parham; Üç, Eda M; Gulçin, Ilhami.

Afiliação

Mirzazadeh R; Department of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.
Asgari MS; Department of Chemistry, Iran University of Science and Technology, Tehran, Iran.
Barzegari E; Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Pedrood K; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohammadi-Khanaposhtani M; Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Sherafati M; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Larijani B; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Rastegar H; Cosmetic Products Research Center, Iranian Food and Drug Administration, MOHE, Tehran, Iran.
Rahmani H; Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Mahdavi M; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Taslimi P; Department of Biotechnology, Faculty of Science, Bartin University, Bartin, Turkey.
Üç EM; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum, Turkey.
Gulçin I; Department of Chemistry, Faculty of Science, Ataturk University, Erzurum, Turkey.

Arch Pharm (Weinheim) ; 354(9): e2000471, 2021 Sep.

Article em En | MEDLINE | ID: mdl-33999440

Assuntos

Oxidiazóis/farmacologia; Quinoxalinas/farmacologia; Inibidores da Anidrase Carbônica/síntese química; Inibidores da Anidrase Carbônica/química; Inibidores da Anidrase Carbônica/farmacologia; Inibidores da Colinesterase/síntese química; Inibidores da Colinesterase/química; Inibidores da Colinesterase/farmacologia; Inibidores de Glicosídeo Hidrolases/síntese química; Inibidores de Glicosídeo Hidrolases/química; Inibidores de Glicosídeo Hidrolases/farmacologia; Humanos; Modelos Moleculares; Simulação de Acoplamento Molecular; Oxidiazóis/síntese química; Oxidiazóis/química; Quinoxalinas/síntese química; Quinoxalinas/química; Relação Estrutura-Atividade

Palavras-chave

1,3,4-oxadiazole; carbonic anhydrase; cholinesterase; quinoxalin; α-glucosidase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Quinoxalinas Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Quinoxalinas Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article