Differentiation and Regulation of T<sub>H</sub> Cells: A Balancing Act for Cancer Immunotherapy.

Basu, Amrita; Ramamoorthi, Ganesan; Albert, Gabriella; Gallen, Corey; Beyer, Amber; Snyder, Colin; Koski, Gary; Disis, Mary L; Czerniecki, Brian J; Kodumudi, Krithika

Differentiation and Regulation of T_H Cells: A Balancing Act for Cancer Immunotherapy.

Basu, Amrita; Ramamoorthi, Ganesan; Albert, Gabriella; Gallen, Corey; Beyer, Amber; Snyder, Colin; Koski, Gary; Disis, Mary L; Czerniecki, Brian J; Kodumudi, Krithika.

Afiliação

Basu A; Clinical Science Division, Moffitt Cancer Center, Tampa, FL, United States.
Ramamoorthi G; Clinical Science Division, Moffitt Cancer Center, Tampa, FL, United States.
Albert G; Clinical Science Division, Moffitt Cancer Center, Tampa, FL, United States.
Gallen C; Clinical Science Division, Moffitt Cancer Center, Tampa, FL, United States.
Beyer A; Clinical Science Division, Moffitt Cancer Center, Tampa, FL, United States.
Snyder C; Clinical Science Division, Moffitt Cancer Center, Tampa, FL, United States.
Koski G; Department of Biological Sciences, Kent State University, Kent, OH, United States.
Disis ML; UW Medicine Cancer Vaccine Institute, University of Washington, Seattle, WA, United States.
Czerniecki BJ; Clinical Science Division, Moffitt Cancer Center, Tampa, FL, United States.
Kodumudi K; Department of Oncological Sciences, University of South Florida, Tampa, FL, United States.

Front Immunol ; 12: 669474, 2021.

Article em En | MEDLINE | ID: mdl-34012451

Assuntos

Imunoterapia; Linfócitos do Interstício Tumoral/imunologia; Neoplasias/terapia; Linfócitos T Citotóxicos/imunologia; Linfócitos T Auxiliares-Indutores/imunologia; Microambiente Tumoral/imunologia; Animais; Antígenos de Neoplasias/metabolismo; Vacinas Anticâncer/uso terapêutico; Diferenciação Celular; Citocinas/metabolismo; Citotoxicidade Imunológica; Humanos; Imunoterapia/efeitos adversos; Imunoterapia Adotiva; Ativação Linfocitária; Linfócitos do Interstício Tumoral/metabolismo; Neoplasias/imunologia; Neoplasias/metabolismo; Neoplasias/patologia; Fenótipo; Transdução de Sinais; Linfócitos T Citotóxicos/metabolismo; Linfócitos T Auxiliares-Indutores/metabolismo

Palavras-chave

CD4; T helper; immunotherapy; neoantigen; tumor associated antigen

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T Citotóxicos / Linfócitos do Interstício Tumoral / Linfócitos T Auxiliares-Indutores / Microambiente Tumoral / Imunoterapia / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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