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Improvement of tacrolimus production in Streptomyces tsukubaensis by mutagenesis and optimization of fermentation medium using Plackett-Burman design combined with response surface methodology.
Yan, Lingbin; Zhang, Zhulan; Zhang, Yin; Yang, Huangjian; Qiu, Guanrong; Wang, Desen; Lian, Yunyang.
Afiliação
  • Yan L; Fujian Provincial Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology, Fuzhou, 350007, China.
  • Zhang Z; Fujian Provincial Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology, Fuzhou, 350007, China. jessylan9963@sina.com.
  • Zhang Y; Fujian Provincial Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology, Fuzhou, 350007, China.
  • Yang H; Fujian Provincial Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology, Fuzhou, 350007, China.
  • Qiu G; Fujian Provincial Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology, Fuzhou, 350007, China.
  • Wang D; Fujian Provincial Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology, Fuzhou, 350007, China.
  • Lian Y; Fujian Provincial Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology, Fuzhou, 350007, China. yylianfim@139.com.
Biotechnol Lett ; 43(9): 1765-1778, 2021 Sep.
Article em En | MEDLINE | ID: mdl-34021830
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Streptomyces / Mutagênese / Tacrolimo Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Streptomyces / Mutagênese / Tacrolimo Idioma: En Ano de publicação: 2021 Tipo de documento: Article