Smartphone-based remote monitoring of vision in macular disease enables early detection of worsening pathology and need for intravitreal therapy.
BMJ Health Care Inform
; 28(1)2021 May.
Article
em En
| MEDLINE
| ID: mdl-34035050
ABSTRACT
BACKGROUND/AIMS:
To assess the outcomes of home monitoring of distortion caused by macular diseases using a smartphone-based application (app), and to examine them with hospital-based assessments of visual acuity (VA), optical coherence tomography-derived central macular thickness (CMT) and the requirement of intravitreal injection therapy.DESIGN:
Observational study with retrospective analysis of data.METHODS:
Participants were trained in the correct use of the app (Alleye, Oculocare, Zurich, Switzerland) in person or by using video and telephone consultations. Automated threshold-based alerts were communicated based on a traffic light system. A 'threshold alarm' was defined as three consecutive 'red' scores, and turned into a 'persistent alarm' if present for greater than a 7-day period. Changes of VA and CMT, and the requirement for intravitreal therapy after an alarm were examined.RESULTS:
245 patients performing a total of 11 592 tests (mean 46.9 tests per user) were included and 85 eyes (164 alarms) examined. Mean drop in VA from baseline was -4.23 letters (95% CI -6.24 to -2.22; p<0.001) and mean increase in CMT was 29.5 µm (95% CI -0.08 to 59.13; p=0.051). Sixty-six eyes (78.5%) producing alarms either had a drop in VA, increase in CMT or both and 60.0% received an injection. Eyes with persistent alarms had a greater loss of VA, -4.79 letters (95% CI -6.73 to -2.85; p<0.001) or greater increase in CMT, +87.8 µm (95% CI 5.2 to 170.4; p=0.038).CONCLUSION:
Smartphone-based self-tests for macular disease may serve as reliable indicators for the worsening of pathology and the need for treatment.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Acuidade Visual
/
Consulta Remota
/
Injeções Intravítreas
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Smartphone
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Degeneração Macular
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Screening_studies
Limite:
Aged
/
Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article