Senescence of donor cells impairs fat graft regeneration by suppressing adipogenesis and increasing expression of senescence-associated secretory phenotype factors.

Chen, Xihang; Feng, Jingwei; Chang, Qiang; Lu, Feng; Yuan, Yi

Chen, Xihang; Feng, Jingwei; Chang, Qiang; Lu, Feng; Yuan, Yi.

Afiliação

Chen X; Department of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, 510515, Guangdong, China.
Feng J; Department of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, 510515, Guangdong, China.
Chang Q; Department of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, 510515, Guangdong, China.
Lu F; Department of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, 510515, Guangdong, China. doctorlufeng@hotmail.com.
Yuan Y; Department of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, 510515, Guangdong, China. yuanyinfyy@outlook.com.

Stem Cell Res Ther ; 12(1): 311, 2021 05 29.

Article em En | MEDLINE | ID: mdl-34051860

Assuntos

Adipogenia; Células-Tronco Mesenquimais; Tecido Adiposo; Animais; Diferenciação Celular; Células Cultivadas; Senescência Celular; Camundongos

Palavras-chave

Adipogenesis; Adipose-derived mesenchymal stem cells; Donor age; Fat grafting; Senescence-associated secretory phenotype

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adipogenia / Células-Tronco Mesenquimais Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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