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mTOR deletion in neural crest cells disrupts cardiac outflow tract remodeling and causes a spectrum of cardiac defects through the mTORC1 pathway.
Nie, Xuguang; Ricupero, Christopher L; Jiao, Kai; Yang, Peixin; Mao, Jeremy J.
Afiliação
  • Nie X; Center for Birth Defects Research,Department of Obstetrics, Gynecology & Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA; College of Dental Medicine, Columbia University in the City of New York, New York, NY, USA. Electronic address: xnie1@umaryland.edu.
  • Ricupero CL; College of Dental Medicine, Columbia University in the City of New York, New York, NY, USA.
  • Jiao K; University of Alabama at Birmingham, Department of Genetics and Genomic Sciences, Birmingham, AL, USA.
  • Yang P; Center for Birth Defects Research,Department of Obstetrics, Gynecology & Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Mao JJ; College of Dental Medicine, Columbia University in the City of New York, New York, NY, USA. Electronic address: jm2654@cumc.columbia.edu.
Dev Biol ; 477: 241-250, 2021 09.
Article em En | MEDLINE | ID: mdl-34052210
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anormalidades Cardiovasculares / Serina-Treonina Quinases TOR / Alvo Mecanístico do Complexo 1 de Rapamicina / Coração / Miocárdio / Crista Neural Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anormalidades Cardiovasculares / Serina-Treonina Quinases TOR / Alvo Mecanístico do Complexo 1 de Rapamicina / Coração / Miocárdio / Crista Neural Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article