The Multifaceted Nature of Nucleobindin-2 in Carcinogenesis.
Int J Mol Sci
; 22(11)2021 May 26.
Article
em En
| MEDLINE
| ID: mdl-34073612
ABSTRACT
Nucb2 is a multifunctional protein associated with a variety of biological processes. Multiple studies have revealed that Nucb2, and its derivative nesfatin-1, are involved in carcinogenesis. Interestingly, the role of Nucb2/nesfatin-1 in tumorigenesis seems to be dual-both pro-metastatic and anti-metastatic. The implication of Nucb2/nesfatin-1 in carcinogenesis seems to be tissue dependent. Herein, we review the role of Nucb2/nesfatin-1 in both carcinogenesis and the apoptosis process, and we also highlight the multifaceted nature of Nucb2/nesfatin-1.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Apoptose
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Carcinogênese
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Proteínas de Neoplasias
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Neoplasias
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article