Effect of cardiac resynchronization therapy on ambulatory blood pressure monitoring indices in patients with heart failure and hypertension.

ABSTRACT

OBJECTIVE: Blood pressure (BP) variability is associated with increased mortality in patients with hypertension and heart failure. The aim of our study was to evaluate the effect of cardiac resynchronization therapy (CRT) on different parameters of 24-h ambulatory blood pressure monitoring (ABPM) in patients with hypertension and heart failure. METHODS: Patients with heart failure and hypertension who were candidate for CRT implantation were enrolled in our study. Twenty-four hour ABPM was performed before, and 6 months after CRT implantation. BP variables and average real variability (ARV) were compared in all patients. RESULT: Sixteen consecutive patients entered our study. There was a significant increase in ARV following CRT implantation (P value = 0.009). CONCLUSION: CRT implantation is associated with increased ARV, but the effect of this improvement on cardiovascular outcome needs more investigation.