Rheb-mTOR activation rescues Aß-induced cognitive impairment and memory function by restoring miR-146 activity in glial cells.

De, Dipayan; Mukherjee, Ishita; Guha, Subhalakshmi; Paidi, Ramesh Kumar; Chakrabarti, Saikat; Biswas, Subhas C; Bhattacharyya, Suvendra N.

Afiliação

De D; RNA Biology Research Laboratory, Molecular Genetics Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
Mukherjee I; Structural Biology and Bio-informatics Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
Guha S; Cell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
Paidi RK; Cell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
Chakrabarti S; Structural Biology and Bio-informatics Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
Biswas SC; Cell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
Bhattacharyya SN; RNA Biology Research Laboratory, Molecular Genetics Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.

Mol Ther Nucleic Acids ; 24: 868-887, 2021 Jun 04.

Article em En | MEDLINE | ID: mdl-34094708