Mass spectrometry-based urinary metabolomics for exploring the treatment effects of Radix ginseng-Schisandra chinensis herb pair on Alzheimer's disease in rats.

Wang, Aimin; Pi, Zifeng; Liu, Shu; Zheng, Zhong; Liu, Zhiqiang; Song, Fengrui

Wang, Aimin; Pi, Zifeng; Liu, Shu; Zheng, Zhong; Liu, Zhiqiang; Song, Fengrui.

Afiliação

Wang A; State Key Laboratory of Electroanalytical Chemistry, National Center of Mass Spectrometry in Changchun, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, P. R. China.
Pi Z; School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, P. R. China.
Liu S; State Key Laboratory of Electroanalytical Chemistry, National Center of Mass Spectrometry in Changchun, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, P. R. China.
Zheng Z; State Key Laboratory of Electroanalytical Chemistry, National Center of Mass Spectrometry in Changchun, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, P. R. China.
Liu Z; State Key Laboratory of Electroanalytical Chemistry, National Center of Mass Spectrometry in Changchun, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, P. R. China.
Song F; State Key Laboratory of Electroanalytical Chemistry, National Center of Mass Spectrometry in Changchun, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, P. R. China.

J Sep Sci ; 44(16): 3158-3166, 2021 Aug.

Article em En | MEDLINE | ID: mdl-34110709

Assuntos

Doença de Alzheimer/metabolismo; Espectrometria de Massas/métodos; Metabolômica/métodos; Panax/metabolismo; Extratos Vegetais/química; Schisandra/metabolismo; Urinálise/métodos; Doença de Alzheimer/tratamento farmacológico; Animais; Biomarcadores/metabolismo; Encéfalo/patologia; Modelos Animais de Doenças; Medicamentos de Ervas Chinesas/química; Microbioma Gastrointestinal; Inflamação; Medicina Tradicional Chinesa; Sistema Nervoso/metabolismo; Fenilalanina/análise; Ratos; Reprodutibilidade dos Testes; Espectrometria de Massas em Tandem/métodos; Tirosina/química

Palavras-chave

Alzheimer's disease; mass spectrometry; metabolic pathways; traditional Chinese medicine; urinary metabolomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Extratos Vegetais / Urinálise / Schisandra / Metabolômica / Doença de Alzheimer / Panax Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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