Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein.

Tetter, Stephan; Terasaka, Naohiro; Steinauer, Angela; Bingham, Richard J; Clark, Sam; Scott, Andrew J P; Patel, Nikesh; Leibundgut, Marc; Wroblewski, Emma; Ban, Nenad; Stockley, Peter G; Twarock, Reidun; Hilvert, Donald

Tetter, Stephan; Terasaka, Naohiro; Steinauer, Angela; Bingham, Richard J; Clark, Sam; Scott, Andrew J P; Patel, Nikesh; Leibundgut, Marc; Wroblewski, Emma; Ban, Nenad; Stockley, Peter G; Twarock, Reidun; Hilvert, Donald.

Afiliação

Tetter S; Laboratory of Organic Chemistry, ETH Zurich, 8093 Zurich, Switzerland.
Terasaka N; Laboratory of Organic Chemistry, ETH Zurich, 8093 Zurich, Switzerland.
Steinauer A; Laboratory of Organic Chemistry, ETH Zurich, 8093 Zurich, Switzerland.
Bingham RJ; Departments of Mathematics and Biology, University of York, York YO10 5DD, UK.
Clark S; Departments of Mathematics and Biology, University of York, York YO10 5DD, UK.
Scott AJP; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Patel N; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Leibundgut M; Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland.
Wroblewski E; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Ban N; Institute of Molecular Biology and Biophysics, ETH Zurich, 8093 Zurich, Switzerland.
Stockley PG; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Twarock R; Departments of Mathematics and Biology, University of York, York YO10 5DD, UK.
Hilvert D; Laboratory of Organic Chemistry, ETH Zurich, 8093 Zurich, Switzerland. donald.hilvert@org.chem.ethz.ch.

Science ; 372(6547): 1220-1224, 2021 06 11.

Article em En | MEDLINE | ID: mdl-34112695

Assuntos

Proteínas de Bactérias/genética; Proteínas de Bactérias/metabolismo; Capsídeo/metabolismo; Evolução Molecular Direcionada; RNA Mensageiro/metabolismo; Substituição de Aminoácidos; Aquifex/enzimologia; Proteínas de Bactérias/química; Capsídeo/química; Microscopia Crioeletrônica; Complexos Multienzimáticos/química; Complexos Multienzimáticos/genética; Complexos Multienzimáticos/metabolismo; Nucleocapsídeo/química; Nucleocapsídeo/genética; Nucleocapsídeo/metabolismo; Domínios Proteicos; Estrutura Secundária de Proteína; Subunidades Proteicas; RNA Mensageiro/química; RNA Mensageiro/genética; Ribonucleases/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / RNA Mensageiro / Capsídeo / Evolução Molecular Direcionada Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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