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Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells.
Taylor, Isabelle R; Assimon, Victoria A; Kuo, Szu Yu; Rinaldi, Silvia; Li, Xiaokai; Young, Zapporah T; Morra, Giulia; Green, Keith; Nguyen, Daniel; Shao, Hao; Garneau-Tsodikova, Sylvie; Colombo, Giorgio; Gestwicki, Jason E.
Afiliação
  • Taylor IR; Department of Pharmaceutical Chemistry, University of California at San Francisco 675 Nelson Rising Lane San Francisco CA 94158 USA jason.gestwicki@ucsf.edu.
  • Assimon VA; Department of Pharmaceutical Chemistry, University of California at San Francisco 675 Nelson Rising Lane San Francisco CA 94158 USA jason.gestwicki@ucsf.edu.
  • Kuo SY; Department of Pharmaceutical Chemistry, University of California at San Francisco 675 Nelson Rising Lane San Francisco CA 94158 USA jason.gestwicki@ucsf.edu.
  • Rinaldi S; Istituto di Chimica del Riconoscimento Molecolare, CNR Via Mario Bianco 9 20131 Milano Italy.
  • Li X; Department of Pharmaceutical Chemistry, University of California at San Francisco 675 Nelson Rising Lane San Francisco CA 94158 USA jason.gestwicki@ucsf.edu.
  • Young ZT; Department of Pharmaceutical Chemistry, University of California at San Francisco 675 Nelson Rising Lane San Francisco CA 94158 USA jason.gestwicki@ucsf.edu.
  • Morra G; Istituto di Chimica del Riconoscimento Molecolare, CNR Via Mario Bianco 9 20131 Milano Italy.
  • Green K; Department of Pharmaceutical Sciences, University of Kentucky Lexington KY 40536-0596 USA.
  • Nguyen D; Department of Pharmaceutical Chemistry, University of California at San Francisco 675 Nelson Rising Lane San Francisco CA 94158 USA jason.gestwicki@ucsf.edu.
  • Shao H; Department of Pharmaceutical Chemistry, University of California at San Francisco 675 Nelson Rising Lane San Francisco CA 94158 USA jason.gestwicki@ucsf.edu.
  • Garneau-Tsodikova S; Department of Pharmaceutical Sciences, University of Kentucky Lexington KY 40536-0596 USA.
  • Colombo G; Istituto di Chimica del Riconoscimento Molecolare, CNR Via Mario Bianco 9 20131 Milano Italy.
  • Gestwicki JE; Department of Chemistry, University of Pavia V.le Taramelli 12 27100 Pavia Italy g.colombo@unipv.it.
Chem Sci ; 11(7): 1892-1904, 2020 Jan 10.
Article em En | MEDLINE | ID: mdl-34123282
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article