Tailoring minimal synthetic receptors to reconstitute signaling properties through multiple tyrosine motifs.

Nakajima, Kyoko; Araki, Shota; Kawahara, Masahiro

Nakajima, Kyoko; Araki, Shota; Kawahara, Masahiro.

Afiliação

Nakajima K; Laboratory of Cell Vaccine, Center for Vaccine and Adjuvant Research (CVAR), National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki-shi, Osaka, 567-0085, Japan.
Araki S; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Kawahara M; Laboratory of Cell Vaccine, Center for Vaccine and Adjuvant Research (CVAR), National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki-shi, Osaka, 567-0085, Japan; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan. Electronic address: m-kawahara@nibiohn.go.jp.

Biochem Biophys Res Commun ; 566: 148-154, 2021 08 20.

Article em En | MEDLINE | ID: mdl-34126345

Assuntos

Receptores Artificiais/química; Tirosina/química; Animais; Linhagem Celular; Camundongos; Multimerização Proteica; Transdução de Sinais; Biologia Sintética; Proteínas de Ligação a Tacrolimo/química

Palavras-chave

Dimerization; Linker; Signal transduction; Synthetic receptor; Tyrosine motif

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tirosina / Receptores Artificiais Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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