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STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma.
Adane, Biniam; Alexe, Gabriela; Seong, Bo Kyung A; Lu, Diana; Hwang, Elizabeth E; Hnisz, Denes; Lareau, Caleb A; Ross, Linda; Lin, Shan; Dela Cruz, Filemon S; Richardson, Melissa; Weintraub, Abraham S; Wang, Sarah; Iniguez, Amanda Balboni; Dharia, Neekesh V; Conway, Amy Saur; Robichaud, Amanda L; Tanenbaum, Benjamin; Krill-Burger, John M; Vazquez, Francisca; Schenone, Monica; Berman, Jason N; Kung, Andrew L; Carr, Steven A; Aryee, Martin J; Young, Richard A; Crompton, Brian D; Stegmaier, Kimberly.
Afiliação
  • Adane B; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Alexe G; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Bioinformatics Graduate Program, Boston University, Boston, MA, USA.
  • Seong BKA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Lu D; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
  • Hwang EE; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
  • Hnisz D; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
  • Lareau CA; Department of Pathology, Stanford University, Stanford, CA, USA.
  • Ross L; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
  • Lin S; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
  • Dela Cruz FS; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Richardson M; Department of Pathology, Dalhousie University, Halifax, NS, Canada.
  • Weintraub AS; Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Wang S; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
  • Iniguez AB; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
  • Dharia NV; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Conway AS; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
  • Robichaud AL; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.
  • Tanenbaum B; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Krill-Burger JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Vazquez F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Schenone M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Berman JN; Department of Pediatrics and Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
  • Kung AL; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Carr SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Aryee MJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Pathology, Massachusetts General Hospital, Charlestown, MA, USA.
  • Young RA; Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Crompton BD; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: briand_crompton@dfci.harvard.edu.
  • Stegmaier K; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: kimberly_stegmaier@dfci.harvard.edu.
Cancer Cell ; 39(6): 827-844.e10, 2021 06 14.
Article em En | MEDLINE | ID: mdl-34129824

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Neoplasias Ósseas / Proteínas de Ciclo Celular Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing / Neoplasias Ósseas / Proteínas de Ciclo Celular Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article