Platelets enhance CD4+ central memory T cell responses via platelet factor 4-dependent mitochondrial biogenesis and cell proliferation.

Tan, Shuai; Zhang, Junhao; Sun, Yang; Gisterå, Anton; Sheng, Zi; Malmström, Rickard E; Hou, Ming; Peng, Jun; Ma, Chunhong; Liao, Wangjun; Li, Nailin

Tan, Shuai; Zhang, Junhao; Sun, Yang; Gisterå, Anton; Sheng, Zi; Malmström, Rickard E; Hou, Ming; Peng, Jun; Ma, Chunhong; Liao, Wangjun; Li, Nailin.

Afiliação

Tan S; Karolinska Institutet, Stockholm, Sweden.
Zhang J; Clinical Epidemiology Unit, Clinical Pharmacology Group, Stockholm, Sweden.
Sun Y; Karolinska Institutet, Stockholm, Sweden.
Gisterå A; Clinical Epidemiology Unit, Clinical Pharmacology Group, Stockholm, Sweden.
Sheng Z; Nanfang Hospital, Department of Oncology, Southern Medical University, Guangzhou, China.
Malmström RE; Shandong University Cheeloo Medical College, School of Basic Medicine, Department of Immunology, Jinan, China.
Hou M; Karolinska Institutet, Stockholm, Sweden.
Peng J; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.
Ma C; Department of Hematology, Qilu Hospital of Shandong University, Jinan, China.
Liao W; Clinical Epidemiology Unit, Clinical Pharmacology Group, Stockholm, Sweden.
Li N; Department of Laboratory Medicine, Clinical Pharmacology, Karolinska University Hospital-Solna, Stockholm, Sweden.

Platelets ; 33(3): 360-370, 2022 Apr 03.

Article em En | MEDLINE | ID: mdl-34137652

Assuntos

Plaquetas/metabolismo; Linfócitos T CD4-Positivos/metabolismo; Células T de Memória/metabolismo; Fator Plaquetário 4/imunologia; Adulto; Proliferação de Células; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Biogênese de Organelas; Adulto Jovem

Palavras-chave

Blood platelets; CD4-positive T central memory cells; CXCR3 receptor; mitochondria; platelet factor 4

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plaquetas / Fator Plaquetário 4 / Linfócitos T CD4-Positivos / Células T de Memória Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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