Non-invasive imaging for the diagnosis of acute rejection in transplantation: The next frontier.
Transpl Immunol
; 68: 101431, 2021 10.
Article
em En
| MEDLINE
| ID: mdl-34157374
ABSTRACT
Acute rejection is a leading cause of organ transplant failure and the most common indication for re-transplantation. Clinically, suspicion of acute rejection is often dependent upon serum laboratory values which may only manifest after organ injury. The gold standard for diagnosis requires an invasive biopsy which can carry serious clinical risks including bleeding and graft loss as well as the possibility of sampling error. The use of noninvasive imaging modalities to monitor transplanted organs is of great clinical value, particularly as a tool for early detection of graft dysfunction or acute rejection. Herein, we provide an overview of the existing literature evaluating noninvasive imaging modalities of solid organ and cellular allografts after transplantation, including both preclinical and clinical studies.
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1
Base de dados:
MEDLINE
Assunto principal:
Transplante de Coração
/
Transplante de Rim
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article