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The effect of water on the large-scale supercritical fluid chromatography purification of two factor XIa active pharmaceutical ingredients.
Li, Peng; Wu, Dauh-Rurng; Yip, Henry; Sun, Dawn; Zhang, Huiping; Hou, Xiaoping; Kempson, James; Mathur, Arvind.
Afiliação
  • Li P; Department of Discovery Synthesis, Bristol Myers Squibb Research and Early Development, Route 206 & Province Line Rd, Princeton, NJ 08543-4000, United States.
  • Wu DR; Department of Discovery Synthesis, Bristol Myers Squibb Research and Early Development, Route 206 & Province Line Rd, Princeton, NJ 08543-4000, United States. Electronic address: dauh-rurng.wu@bms.com.
  • Yip H; Department of Discovery Synthesis, Bristol Myers Squibb Research and Early Development, Route 206 & Province Line Rd, Princeton, NJ 08543-4000, United States.
  • Sun D; Department of Discovery Synthesis, Bristol Myers Squibb Research and Early Development, Route 206 & Province Line Rd, Princeton, NJ 08543-4000, United States.
  • Zhang H; Department of Discovery Synthesis, Bristol Myers Squibb Research and Early Development, Route 206 & Province Line Rd, Princeton, NJ 08543-4000, United States.
  • Hou X; Department of Discovery Synthesis, Bristol Myers Squibb Research and Early Development, Route 206 & Province Line Rd, Princeton, NJ 08543-4000, United States.
  • Kempson J; Department of Discovery Synthesis, Bristol Myers Squibb Research and Early Development, Route 206 & Province Line Rd, Princeton, NJ 08543-4000, United States.
  • Mathur A; Department of Discovery Synthesis, Bristol Myers Squibb Research and Early Development, Route 206 & Province Line Rd, Princeton, NJ 08543-4000, United States.
J Chromatogr A ; 1651: 462318, 2021 Aug 16.
Article em En | MEDLINE | ID: mdl-34161834
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Água / Fator XIa / Cromatografia com Fluido Supercrítico Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Água / Fator XIa / Cromatografia com Fluido Supercrítico Idioma: En Ano de publicação: 2021 Tipo de documento: Article