Developmental regulation of two 5S ribosomal RNA genes.
Science
; 241(4873): 1626-32, 1988 Sep 23.
Article
em En
| MEDLINE
| ID: mdl-3420414
ABSTRACT
The developmental regulation of two kinds of Xenopus 5S RNA genes (oocyte and somatic types) can be explained by differences in the stability of protein-protein and protein-DNA interactions in a transcription complex that directs transcription initiation by RNA polymerase III. Dissociation of transcription factors from oocyte 5S RNA genes during development allows them to be repressed by chromatin assembly. In the same cells, somatic 5S RNA genes remain active because their transcription complexes are stable.
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Base de dados:
MEDLINE
Assunto principal:
RNA Ribossômico
/
RNA Ribossômico 5S
/
Regulação da Expressão Gênica
/
Fatores de Transcrição TFIII
Limite:
Animals
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article