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Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.
Godyn, Justyna; Zareba, Paula; Lazewska, Dorota; Stary, Dorota; Reiner-Link, David; Frank, Annika; Latacz, Gniewomir; Mogilski, Szczepan; Kaleta, Maria; Doroz-Plonka, Agata; Lubelska, Annamaria; Honkisz-Orzechowska, Ewelina; Olejarz-Maciej, Agnieszka; Handzlik, Jadwiga; Stark, Holger; Kiec-Kononowicz, Katarzyna; Malawska, Barbara; Bajda, Marek.
Afiliação
  • Godyn J; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Zareba P; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Lazewska D; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Stary D; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Reiner-Link D; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Duesseldorf, Universitaetsstr. 1, Duesseldorf 40225, Germany.
  • Frank A; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Duesseldorf, Universitaetsstr. 1, Duesseldorf 40225, Germany.
  • Latacz G; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Mogilski S; Department of Pharmacodynamics, Jagiellonian University Medical College, Medyczna 9, Kraków 30-688, Poland.
  • Kaleta M; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Doroz-Plonka A; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Lubelska A; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Honkisz-Orzechowska E; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Olejarz-Maciej A; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Handzlik J; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Stark H; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Duesseldorf, Universitaetsstr. 1, Duesseldorf 40225, Germany.
  • Kiec-Kononowicz K; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Malawska B; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland.
  • Bajda M; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Medyczna 9, Krakow 30-688, Poland. Electronic address: marek.bajda@uj.edu.pl.
Bioorg Chem ; 114: 105129, 2021 09.
Article em En | MEDLINE | ID: mdl-34217977
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Bifenilo / Inibidores da Colinesterase / Receptores Histamínicos H3 / Doença de Alzheimer / Inibidores da Monoaminoxidase Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Bifenilo / Inibidores da Colinesterase / Receptores Histamínicos H3 / Doença de Alzheimer / Inibidores da Monoaminoxidase Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article