Spontaneous resolution of schitic cavities in XLRS.
Ophthalmic Genet
; 42(6): 765-767, 2021 12.
Article
em En
| MEDLINE
| ID: mdl-34223802
ABSTRACT
X-linked retinoschisis (XLRS) is an inherited retinal condition that leads to schisis of the retina. In the past, treatment trials for XLRS have generally used OCT monitoring of the schitic cavities as the primary structural outcome measure and best corrected visual acuity as the primary functional outcome. Here, we report two cases of genetically confirmed XLRS with marked fluctuations in OCT morphology in the absence of treatment. Given this demonstration of spontaneous fluctuation in retinal structure on OCT in XLRS we suggest that alternative measures of retinal function should be used in future therapeutic trials in XLRS.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Retina
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Polimorfismo de Nucleotídeo Único
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Retinosquise
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Proteínas do Olho
Tipo de estudo:
Prognostic_studies
Limite:
Adult
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Child
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Humans
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Male
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article