Pomegranate Polyphenols Attenuate Inflammation and Hepatic Damage in Tumor-Bearing Mice: Crucial Role of NF-&#954;B and the Nrf2/GSH Axis.

Mukherjee, Sudeshna; Ghosh, Sayan; Choudhury, Sreetama; Gupta, Payal; Adhikary, Arghya; Chattopadhyay, Sreya

Pomegranate Polyphenols Attenuate Inflammation and Hepatic Damage in Tumor-Bearing Mice: Crucial Role of NF-κB and the Nrf2/GSH Axis.

Mukherjee, Sudeshna; Ghosh, Sayan; Choudhury, Sreetama; Gupta, Payal; Adhikary, Arghya; Chattopadhyay, Sreya.

Afiliação

Mukherjee S; Department of Physiology, University of Calcutta; Kolkata, India.
Ghosh S; Department of Physiology, University of Calcutta; Kolkata, India.
Choudhury S; Department of Physiology, University of Calcutta; Kolkata, India.
Gupta P; Department of Physiology, University of Calcutta; Kolkata, India.
Adhikary A; Centre for Research in Nanoscience and Nanotechnology, University of Calcutta, Kolkata, India.
Chattopadhyay S; Department of Physiology, University of Calcutta; Kolkata, India; Centre for Research in Nanoscience and Nanotechnology, University of Calcutta, Kolkata, India. Electronic address: sreyasaha@gmail.com.

J Nutr Biochem ; 97: 108812, 2021 11.

Article em En | MEDLINE | ID: mdl-34224820

Assuntos

Carcinoma de Ehrlich/complicações; Glutationa/metabolismo; Hepatopatias/prevenção & controle; Fator 2 Relacionado a NF-E2/metabolismo; NF-kappa B/metabolismo; Polifenóis/administração & dosagem; Punica granatum; Animais; Antioxidantes/metabolismo; Carcinoma de Ehrlich/metabolismo; Citocinas/metabolismo; Suplementos Nutricionais; Feminino; Hepatócitos/fisiologia; Inflamação; Fígado/metabolismo; Hepatopatias/etiologia; Hepatopatias/metabolismo; Hepatopatias/patologia; Camundongos; Estresse Oxidativo; Extratos Vegetais/administração & dosagem

Palavras-chave

Apoptosis; Cancer; Hepatotoxicity; Inflammation; NF-κB; Nrf2; Pomegranate; Reactive oxygen species

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Ehrlich / NF-kappa B / Fator 2 Relacionado a NF-E2 / Polifenóis / Punica granatum / Glutationa / Hepatopatias Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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