Cytokine-based Cancer Immunotherapy: Challenges and Opportunities for IL-10.

Rallis, Kathrine S; Corrigan, Amber E; Dadah, Hashim; George, Alan Mathew; Keshwara, Sumirat M; Sideris, Michail; Szabados, Bernadett

Rallis, Kathrine S; Corrigan, Amber E; Dadah, Hashim; George, Alan Mathew; Keshwara, Sumirat M; Sideris, Michail; Szabados, Bernadett.

Afiliação

Rallis KS; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, U.K.; k.s.rallis@smd16.qmul.ac.uk.
Corrigan AE; GKT School of Medicine, King's College London, London, U.K.
Dadah H; GKT School of Medicine, King's College London, London, U.K.
George AM; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, U.K.
Keshwara SM; Liverpool School of Medicine, University of Liverpool, Liverpool, U.K.
Sideris M; Liverpool School of Medicine, University of Liverpool, Liverpool, U.K.
Szabados B; Women's Health Research Unit, Queen Mary University of London, London, U.K.

Anticancer Res ; 41(7): 3247-3252, 2021 Jul.

Article em En | MEDLINE | ID: mdl-34230118

Assuntos

Citocinas/farmacologia; Citocinas/uso terapêutico; Interleucina-10/farmacologia; Interleucina-10/uso terapêutico; Neoplasias/imunologia; Neoplasias/terapia; Animais; Humanos; Imunoterapia/métodos; Polimorfismo Genético/efeitos dos fármacos; Microambiente Tumoral/efeitos dos fármacos

Palavras-chave

Cytokines; IL-10; cancer immunotherapy; combination therapy; pegilodecakin; pharmacodynamics (PD); pharmacokinetics (PK); review; single nucleotide polymorphisms (SNPs); tumour microenvironment (TME)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citocinas / Interleucina-10 / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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