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Lead optimization to improve the antiviral potency of 2-aminobenzamide derivatives targeting HIV-1 Vif-A3G axis.
Zhong, Xinxin; Luo, Ronghua; Yan, Guoyi; Ran, Kai; Shan, Huifang; Yang, Jie; Liu, Yuanyuan; Yu, Su; Pu, Chunlan; Zheng, Yongtang; Li, Rui.
Afiliação
  • Zhong X; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China.
  • Luo R; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology,Chinese Academy of Sciences, Kunming, Yunnan, 650223, PR China.
  • Yan G; School of Pharmacy, Henan University, Kaifeng, Henan, 475001, PR China.
  • Ran K; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China.
  • Shan H; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China.
  • Yang J; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China.
  • Liu Y; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China.
  • Yu S; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China.
  • Pu C; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China.
  • Zheng Y; Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology,Chinese Academy of Sciences, Kunming, Yunnan, 650223, PR China. Electronic address: Zhengyt@mail.kiz.ac.cn.
  • Li R; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China. Electronic address: lirui@scu.edu.cn.
Eur J Med Chem ; 224: 113680, 2021 Nov 15.
Article em En | MEDLINE | ID: mdl-34245947
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: HIV-1 / Fármacos Anti-HIV / Produtos do Gene vif do Vírus da Imunodeficiência Humana / Ortoaminobenzoatos / Desaminase APOBEC-3G Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: HIV-1 / Fármacos Anti-HIV / Produtos do Gene vif do Vírus da Imunodeficiência Humana / Ortoaminobenzoatos / Desaminase APOBEC-3G Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article