HDAC1/2 Control Proliferation and Survival in Adult Epidermis and PreâBasal Cell Carcinoma through p16 and p53.

Zhu, Xuming; Leboeuf, Matthew; Liu, Fang; Grachtchouk, Marina; Seykora, John T; Morrisey, Edward E; Dlugosz, Andrzej A; Millar, Sarah E

HDAC1/2 Control Proliferation and Survival in Adult Epidermis and PreâBasal Cell Carcinoma through p16 and p53.

Zhu, Xuming; Leboeuf, Matthew; Liu, Fang; Grachtchouk, Marina; Seykora, John T; Morrisey, Edward E; Dlugosz, Andrzej A; Millar, Sarah E.

Afiliação

Zhu X; Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicin
Leboeuf M; Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Cell & Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Surgery, Geisel School of Medicine
Liu F; Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Grachtchouk M; Department of Dermatology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Seykora JT; Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Morrisey EE; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Dlugosz AA; Department of Dermatology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Millar SE; Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicin

J Invest Dermatol ; 142(1): 77-87.e10, 2022 01.

Article em En | MEDLINE | ID: mdl-34284046

Assuntos

Carcinoma Basocelular/metabolismo; Inibidor p16 de Quinase Dependente de Ciclina/metabolismo; Epiderme/fisiologia; Queratinócitos/fisiologia; Neoplasias Cutâneas/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Animais; Antibióticos Antineoplásicos/farmacologia; Antibióticos Antineoplásicos/uso terapêutico; Apoptose; Carcinogênese; Carcinoma Basocelular/tratamento farmacológico; Carcinoma Basocelular/genética; Diferenciação Celular; Linhagem Celular Tumoral; Proliferação de Células; Inibidor p16 de Quinase Dependente de Ciclina/genética; Depsipeptídeos/farmacologia; Depsipeptídeos/uso terapêutico; Histona Desacetilase 1/antagonistas & inibidores; Histona Desacetilase 1/genética; Histona Desacetilase 2/antagonistas & inibidores; Histona Desacetilase 2/genética; Humanos; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Lesões Pré-Cancerosas; Neoplasias Cutâneas/tratamento farmacológico; Neoplasias Cutâneas/genética; Proteína Supressora de Tumor p53/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Carcinoma Basocelular / Queratinócitos / Proteína Supressora de Tumor p53 / Inibidor p16 de Quinase Dependente de Ciclina / Epiderme Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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