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Structure-Activity Relationships of the Antimalarial Agent Artemisinin 10. Synthesis and Antimalarial Activity of Enantiomers of rac-5ß-Hydroxy-d-Secoartemisinin and Analogs: Implications Regarding the Mechanism of Action.
Jahan, Mohamed; Leon, Francisco; Fronczek, Frank R; Elokely, Khaled M; Rimoldi, John; Khan, Shabana I; Avery, Mitchell A.
Afiliação
  • Jahan M; Department of BioMolecular Sciences, Division Medicinal Chemistry, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
  • Leon F; Department of Drug Discovery and Biomedical Sciences, University of South Carolina, Columbia, SC 29208, USA.
  • Fronczek FR; Department of Chemistry, Louisiana State University, Baton Rouge, LA 70803, USA.
  • Elokely KM; Department of Pharmaceutical Chemistry, Tanta University, Tanta 31527, Egypt.
  • Rimoldi J; Department of Chemistry, Institute for Computational Molecular Science, Temple University, Philadelphia, PA 19122, USA.
  • Khan SI; Department of BioMolecular Sciences, Division Medicinal Chemistry, School of Pharmacy, University of Mississippi, University, MS 38677, USA.
  • Avery MA; National Center for Natural Product Research, University of Mississippi, University, MS 38677, USA.
Molecules ; 26(14)2021 Jul 08.
Article em En | MEDLINE | ID: mdl-34299438
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Artemisininas / Antimaláricos Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Artemisininas / Antimaláricos Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article