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Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans.
Yates, Kathleen B; Tonnerre, Pierre; Martin, Genevieve E; Gerdemann, Ulrike; Al Abosy, Rose; Comstock, Dawn E; Weiss, Sarah A; Wolski, David; Tully, Damien C; Chung, Raymond T; Allen, Todd M; Kim, Arthur Y; Fidler, Sarah; Fox, Julie; Frater, John; Lauer, Georg M; Haining, W Nicholas; Sen, Debattama R.
Afiliação
  • Yates KB; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Tonnerre P; Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
  • Martin GE; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Gerdemann U; Division of Gastroenterology, Liver Center, Massachusetts General Hospital, Boston, MA, USA.
  • Al Abosy R; Inserm U976, Institut de Recherche Saint-Louis, Paris, France.
  • Comstock DE; Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Weiss SA; Department of Infectious Diseases, Central Clinical School, Monash University, Melbourne, Australia.
  • Wolski D; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Tully DC; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Chung RT; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Allen TM; Division of Medical Sciences, Harvard Medical School, Boston, MA, USA.
  • Kim AY; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Fidler S; Division of Medical Sciences, Harvard Medical School, Boston, MA, USA.
  • Fox J; Division of Gastroenterology, Liver Center, Massachusetts General Hospital, Boston, MA, USA.
  • Frater J; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Lauer GM; Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
  • Haining WN; Division of Gastroenterology, Liver Center, Massachusetts General Hospital, Boston, MA, USA.
  • Sen DR; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Nat Immunol ; 22(8): 1020-1029, 2021 08.
Article em En | MEDLINE | ID: mdl-34312547

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepacivirus / Linfócitos T CD8-Positivos / Hepatite C Crônica / Memória Imunológica / Antígenos Virais Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepacivirus / Linfócitos T CD8-Positivos / Hepatite C Crônica / Memória Imunológica / Antígenos Virais Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article