Cascaded valorization of brown seaweed to produce l-lysine and value-added products using Corynebacterium glutamicum streamlined by systems metabolic engineering.

Hoffmann, Sarah Lisa; Kohlstedt, Michael; Jungmann, Lukas; Hutter, Michael; Poblete-Castro, Ignacio; Becker, Judith; Wittmann, Christoph

Hoffmann, Sarah Lisa; Kohlstedt, Michael; Jungmann, Lukas; Hutter, Michael; Poblete-Castro, Ignacio; Becker, Judith; Wittmann, Christoph.

Afiliação

Hoffmann SL; Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany.
Kohlstedt M; Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany.
Jungmann L; Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany.
Hutter M; Centre for Bioinformatics, Saarland University, Saarbrücken, Germany.
Poblete-Castro I; Biosystems Engineering Laboratory, Universidad Andres Bello, Santiago, Chile.
Becker J; Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany.
Wittmann C; Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany. Electronic address: christoph.wittmann@uni-saarland.de.

Metab Eng ; 67: 293-307, 2021 09.

Article em En | MEDLINE | ID: mdl-34314893

Assuntos

Corynebacterium glutamicum; Alga Marinha; Corynebacterium glutamicum/genética; Humanos; Lisina/genética; Engenharia Metabólica; NADP

Palavras-chave

Fructokinase; Fructose; Glyceraldehyde 3-phosphate dehydrogenase; L-lysine; Macro algae; Mannitol 2-dehydrogenase; NADH; NADPH; Oxidative pentose phosphate pathway; Protein engineering; Redox balancing; Seaweed; Transhydrogenase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alga Marinha / Corynebacterium glutamicum Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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