Moderate-to-Vigorous Physical Activity Is Associated With Higher Bone Mineral Density in Children With Inflammatory Bowel Disease.
J Pediatr Gastroenterol Nutr
; 74(1): 54-59, 2022 01 01.
Article
em En
| MEDLINE
| ID: mdl-34321428
ABSTRACT
OBJECTIVES:
Decreased mineral bone density (BMD) and reduced lean body mass (LBM) are common amongst children with inflammatory bowel disease (IBD). The aim of our cross-sectional, observational study was to evaluate the relationship between BMD, body composition and physical activity (PA) in children with IBD in remission.METHODS:
Total body less head (TLBH) dual energy X-ray absorptiometry (DXA) was used to measure BMD, fat mass (FM) and lean body mass (LBM). Triaxial accelerometer for five consecutive days was used to objectivize PA.RESULTS:
Forty pediatric IBD patients in clinical remission (24 boys; age 15.3â±â0.4âyears; Crohn disease [CD], nâ=â20, ulcerative colitis [UC], nâ=â18, inflammatory bowel disease-unclassified [IBD-U], nâ=â2) were recruited. Mean BMD was 0.940âg/cm2 and mean BMD z score was -0.42â±â0.14. Patients with CD had significantly lower BMD than UC counterparts (Pâ<â0.001). Average time spent in PA was 247.24â±â16.71âmin/day with 45.73â±â8.22âmin/day spent in moderate-to-vigorous PA (MVPA). We observed a significant positive correlation between the time spent in MVPA and BMD z score (Pâ=â0.003) and LBM z score (Pâ=â0.026). Multivariate analysis confirmed that the positive correlation of MVPA and BMD z score. There was no significant correlation between daily protein intake and BMD. Cumulative glucocorticoid dose negatively correlated with LBM z score (Pâ=â0.003), but not with BMD z score (Pâ=â0.069).CONCLUSIONS:
This study points to a strong positive relationship between MVPA, LBM and BMD. Longitudinal studies are required in order to elucidate the modifiable processes that determine body health and favorable body composition.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Doenças Inflamatórias Intestinais
/
Densidade Óssea
Tipo de estudo:
Observational_studies
/
Prevalence_studies
Limite:
Adolescent
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Child
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Humans
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Male
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article