A calcium phosphate drug carrier loading with 5-fluorouracil achieving a synergistic effect for pancreatic cancer therapy.

Chen, Junzong; Qiu, Miaojuan; Zhang, Shiqiang; Li, Binbin; Li, Dong; Huang, Xiuyu; Qian, Zhirong; Zhao, Jing; Wang, Zhiyong; Tang, Di

Chen, Junzong; Qiu, Miaojuan; Zhang, Shiqiang; Li, Binbin; Li, Dong; Huang, Xiuyu; Qian, Zhirong; Zhao, Jing; Wang, Zhiyong; Tang, Di.

Afiliação

Chen J; The Seventh Hospital of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.
Qiu M; The Seventh Hospital of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.
Zhang S; The Seventh Hospital of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.
Li B; The Seventh Hospital of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.
Li D; The Seventh Hospital of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.
Huang X; The Seventh Hospital of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.
Qian Z; The Seventh Hospital of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.
Zhao J; The Seventh Hospital of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China. Electronic address: zhaoj265@mail.sysu.edu.cn.
Wang Z; The Seventh Hospital of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China; School of Materials Science and Engineering, Center for Functional Biomaterials, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Guangzhou Key Laboratory of Flexi
Tang D; The Seventh Hospital of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China. Electronic address: tangdi@mail.sysu.edu.cn.

J Colloid Interface Sci ; 605: 263-273, 2022 Jan.

Article em En | MEDLINE | ID: mdl-34332405

Assuntos

Fluoruracila; Neoplasias Pancreáticas; Apoptose; Fosfatos de Cálcio; Linhagem Celular Tumoral; Portadores de Fármacos; Fluoruracila/farmacologia; Humanos; Neoplasias Pancreáticas/tratamento farmacológico

Palavras-chave

Calcium overload; Calcium phosphate; Endoplasmic reticulum stress; Pancreatic cancer; Reactive oxygen species

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Fluoruracila Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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