Eu(III)-DO3A and BODIPY dyad as a chemosensor for anthrax biomarker.

ABSTRACT

The sensitive and selective determination of Bacillus anthracis spores before the infection is vital for human health and safety. Dipicolinic acid (DPA) is an excellent biomarker due to its presence in the nucleus of bacterial spores at high concentrations (up to 1 M, about 15% dry weight). In the present work, a new molecular chemosensor 1, based on europium(III)-DO3A and BODIPY dyad, is developed to detect DPA in phosphate-buffered saline (PBS) buffered solution and tap water samples. Also, 1 can be used as a ratiometric optical chemosensor to track DPA.