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Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol.
Hellwig, Christian T; Delgado, M Eugenia; Skoko, Josip; Dyck, Lydia; Hanna, Carol; Wentges, Alexa; Langlais, Claudia; Hagenlocher, Cathrin; Mack, Alexandra; Dinsdale, David; Cain, Kelvin; MacFarlane, Marion; Rehm, Markus.
Afiliação
  • Hellwig CT; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Delgado ME; Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Skoko J; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
  • Dyck L; Stuttgart Research Center Systems Biology, University of Stuttgart, Stuttgart, Germany.
  • Hanna C; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Wentges A; Centre for Systems Medicine, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Langlais C; Biochemical Pharmacology, Department of Biology, University of Konstanz, Konstanz, Germany.
  • Hagenlocher C; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
  • Mack A; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Dinsdale D; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
  • Cain K; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
  • MacFarlane M; MRC Toxicology Unit, Cambridge, UK.
  • Rehm M; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
Cell Death Differ ; 29(1): 147-155, 2022 01.
Article em En | MEDLINE | ID: mdl-34354257
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Complexo de Endopeptidases do Proteassoma / Receptores do Ligante Indutor de Apoptose Relacionado a TNF Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Complexo de Endopeptidases do Proteassoma / Receptores do Ligante Indutor de Apoptose Relacionado a TNF Idioma: En Ano de publicação: 2022 Tipo de documento: Article