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Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity.
Magliocco, Gaëlle; Desmeules, Jules; Matthey, Alain; Quirós-Guerrero, Luis M; Bararpour, Nasim; Joye, Timothée; Marcourt, Laurence; Queiroz, Emerson F; Wolfender, Jean-Luc; Gloor, Yvonne; Thomas, Aurélien; Daali, Youssef.
Afiliação
  • Magliocco G; Division of Clinical Pharmacology and Toxicology, Geneva University Hospitals, Geneva, Switzerland.
  • Desmeules J; School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
  • Matthey A; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland.
  • Quirós-Guerrero LM; Division of Clinical Pharmacology and Toxicology, Geneva University Hospitals, Geneva, Switzerland.
  • Bararpour N; School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
  • Joye T; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland.
  • Marcourt L; Clinical Research Center, Geneva University Hospitals, Geneva, Switzerland.
  • Queiroz EF; Division of Clinical Pharmacology and Toxicology, Geneva University Hospitals, Geneva, Switzerland.
  • Wolfender JL; Clinical Research Center, Geneva University Hospitals, Geneva, Switzerland.
  • Gloor Y; School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.
  • Thomas A; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Geneva, Switzerland.
  • Daali Y; Forensic Toxicology and Chemistry Unit, CURML, Lausanne University Hospital, Geneva University Hospitals, Lausanne, Geneva, Switzerland.
Br J Pharmacol ; 178(23): 4708-4725, 2021 12.
Article em En | MEDLINE | ID: mdl-34363609
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP2D6 / Metabolômica Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP2D6 / Metabolômica Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article