Human Platelets and Influenza Virus: Internalization and Platelet Activation.
Platelets
; 33(2): 184-191, 2022 Feb 17.
Article
em En
| MEDLINE
| ID: mdl-34369285
ABSTRACT
Influenza infection has long been associated with prothrombotic outcomes in patients and platelets are the blood component predominantly responsible for thrombosis. In this review, we outline what is known about influenza interaction with human platelets, virion internalization, and viral RNA sensing, and the consequent impact on platelet function. We further discuss activation of platelets by IgG-influenza complexes and touch upon mechanisms of environmental platelet activation that relate to prothrombotic outcomes in patients during infection.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Plaquetas
/
Ativação Plaquetária
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Influenza Humana
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article