Effect of protein A on mast cell numbers and macrophage phagocytic activity.
Immunopharmacol Immunotoxicol
; 9(2-3): 281-97, 1987.
Article
em En
| MEDLINE
| ID: mdl-3437103
ABSTRACT
Swiss albino male mice were given Protein A (PA) treatment ip (0, 1.0, 6.0 or 12.0 micrograms per mouse) twice weekly for two weeks. Alterations in white blood cell counts, peritoneal cell number, peritoneal macrophage and mast cell number were found. Macrophage induced phagocytosis of sheep red blood cells was also found enhanced in PA group. The maximum effect was found in 1.0 microgram of PA dose group of mice. From our studies it can be derived that PA induced tumor regression may be due to potentiation of macrophage induced antitumor activity.
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Base de dados:
MEDLINE
Assunto principal:
Fagocitose
/
Proteína Estafilocócica A
/
Macrófagos
/
Mastócitos
Limite:
Animals
Idioma:
En
Ano de publicação:
1987
Tipo de documento:
Article