Deficiency of peroxisome proliferator-activated receptor &#945; attenuates apoptosis and promotes migration of vascular smooth muscle cells.

Duan, Yan; Qi, Dan; Liu, Ye; Song, Yanting; Wang, Xia; Jiao, Shiyu; Li, Huihua; Gonzalez, Frank J; Qi, Yongfen; Xu, Qingbo; Du, Jie; Qu, Aijuan

Deficiency of peroxisome proliferator-activated receptor α attenuates apoptosis and promotes migration of vascular smooth muscle cells.

Duan, Yan; Qi, Dan; Liu, Ye; Song, Yanting; Wang, Xia; Jiao, Shiyu; Li, Huihua; Gonzalez, Frank J; Qi, Yongfen; Xu, Qingbo; Du, Jie; Qu, Aijuan.

Afiliação

Duan Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University; Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education; Beijing, China.
Qi D; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University; Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education; Beijing, China.
Liu Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University; Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education; Beijing, China.
Song Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University; Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education; Beijing, China.
Wang X; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University; Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education; Beijing, China.
Jiao S; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University; Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education; Beijing, China.
Li H; Department of Nutrition and Food Hygiene, School of Public Health, Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Gonzalez FJ; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Qi Y; Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Xu Q; School of Cardiovascular Medicine and Sciences, King' s College of London, London, UK.
Du J; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University; Key Laboratory of Remodeling-Related Cardiovascular Diseases, Ministry of Education; Beijing, China.
Qu A; Beijing Anzhen Hospital of Capital Medical University and Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China.

Biochem Biophys Rep ; 27: 101091, 2021 Sep.

Article em En | MEDLINE | ID: mdl-34381883

Palavras-chave

Ang II, angiotensin II; Angiotensin II; EC, endothelial cell; ECM, extracellular matrix; ERK, extracellular signal-regulated kinase; MAPK, mitogen-activated protein kinase; MCP-1, monocyte chemoattractant protein-1; PCR, polymerase chain reaction; PPAR, peroxisome proliferator-activated receptor; PPARα; SM22α, smooth muscle 22α; TGF, tumor growth factor; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling; VSMC, vascular smooth muscle cell; Vascular remodeling; Vascular smooth muscle cell

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article