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miR-221 confers lapatinib resistance by negatively regulating p27kip1 in HER2-positive breast cancer.
Huynh, Thanh Kieu; Huang, Chih-Hao; Chen, Jhen-Yu; Yao, Jin-Han; Yang, Yi-Shiang; Wei, Ya-Ling; Chen, Hsiao-Fan; Chen, Chia-Hung; Tu, Chih-Yen; Hsu, Yuan-Man; Liu, Liang-Chih; Huang, Wei-Chien.
Afiliação
  • Huynh TK; Graduate Institute of Biomedical Sciences, Drug Development Center, China Medical University, Taichung, Taiwan.
  • Huang CH; Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.
  • Chen JY; Graduate Institute of Biomedical Sciences, Drug Development Center, China Medical University, Taichung, Taiwan.
  • Yao JH; Division of Breast Surgery, China Medical University Hospital, Taichung, Taiwan.
  • Yang YS; Graduate Institute of Biomedical Sciences, Drug Development Center, China Medical University, Taichung, Taiwan.
  • Wei YL; School of Medicine, China Medical University, Taichung, Taiwan.
  • Chen HF; Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.
  • Chen CH; Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.
  • Tu CY; Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.
  • Hsu YM; School of Medicine, China Medical University, Taichung, Taiwan.
  • Liu LC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
  • Huang WC; School of Medicine, China Medical University, Taichung, Taiwan.
Cancer Sci ; 112(10): 4234-4245, 2021 Oct.
Article em En | MEDLINE | ID: mdl-34382727
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Receptor ErbB-2 / Resistencia a Medicamentos Antineoplásicos / MicroRNAs / Inibidor de Quinase Dependente de Ciclina p27 / Lapatinib / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Receptor ErbB-2 / Resistencia a Medicamentos Antineoplásicos / MicroRNAs / Inibidor de Quinase Dependente de Ciclina p27 / Lapatinib / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article