Targeted and Untargeted Mass Spectrometry Reveals the Impact of High-Fat Diet on Peripheral Amino Acid Regulation in a Mouse Model of Alzheimer's Disease.

Taylor, Amelia L; Davis, Don E; Codreanu, Simona G; Harrison, Fiona E; Sherrod, Stacy D; McLean, John A

Taylor, Amelia L; Davis, Don E; Codreanu, Simona G; Harrison, Fiona E; Sherrod, Stacy D; McLean, John A.

Afiliação

Taylor AL; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
Davis DE; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
Codreanu SG; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
Harrison FE; Center for Innovative Technology, Vanderbilt University, Nashville, Tennessee 37235, United States.
Sherrod SD; Vanderbilt University Medical Center, Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, Tennessee 37235, United States.
McLean JA; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.

J Proteome Res ; 20(9): 4405-4414, 2021 09 03.

Article em En | MEDLINE | ID: mdl-34382806

Assuntos

Doença de Alzheimer; Aminoácidos; Animais; Dieta Hiperlipídica/efeitos adversos; Espectrometria de Massas; Metabolômica; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos

Palavras-chave

Alzheimer's disease; amino acid metabolism; high-fat diet; low-fat diet; mass spectrometry; metabolomics; mitochondrial dysfunction; reversal diet

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Tipo de estudo: Guideline Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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