[The route is the destination-novel forms of application of allergen immunotherapy]. / Der Weg ist das Ziel neue Applikationsverfahren der Allergenimmuntherapie.
Hautarzt
; 72(9): 776-783, 2021 Sep.
Article
em De
| MEDLINE
| ID: mdl-34387710
ABSTRACT
Allergen immunotherapy (AIT) is the only causal therapy of IgE-mediated allergies if allergen avoidance is not feasible. Already well established are subcutaneous (SCIT) and sublingual (SLIT) allergen application, and recently the first oral immunotherapy (OIT) for treating peanut allergy was approved. Interesting and promising new forms of allergen administration are intralymphatic (ILIT) and epicutaneous (EPIT) immunotherapy. Immunologic and clinical efficiency in terms of tolerance induction have been investigated in animal and clinical studies, including the first phase 3 studies. The findings as well as advantages and disadvantages, potential risks and challenges that still have to be addressed before routine clinical application can be envisioned will be comprehensively presented and discussed.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Alérgenos
/
Dessensibilização Imunológica
Limite:
Animals
Idioma:
De
Ano de publicação:
2021
Tipo de documento:
Article