Deorphanization of novel biogenic amine-gated ion channels identifies a new serotonin receptor for learning.

Morud, Julia; Hardege, Iris; Liu, He; Wu, Taihong; Choi, Myung-Kyu; Basu, Swaraj; Zhang, Yun; Schafer, William R

Morud, Julia; Hardege, Iris; Liu, He; Wu, Taihong; Choi, Myung-Kyu; Basu, Swaraj; Zhang, Yun; Schafer, William R.

Afiliação

Morud J; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Hardege I; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Liu H; Department of Organismic and Evolutionary Biology, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA; Centre for Brain Science, Harvard University, Cambridge, MA 02138, USA.
Wu T; Department of Organismic and Evolutionary Biology, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA; Centre for Brain Science, Harvard University, Cambridge, MA 02138, USA.
Choi MK; Department of Organismic and Evolutionary Biology, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA; Centre for Brain Science, Harvard University, Cambridge, MA 02138, USA.
Basu S; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Medicinaregatan 9A, University of Gothenburg, 405 30 Gothenburg, Sweden.
Zhang Y; Department of Organismic and Evolutionary Biology, Harvard University, 52 Oxford Street, Cambridge, MA 02138, USA; Centre for Brain Science, Harvard University, Cambridge, MA 02138, USA.
Schafer WR; MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK; Department of Biology, KU Leuven, Naamsestraat 59, 3000 Leuven, Belgium. Electronic address: wschafer@mrc-lmb.cam.ac.uk.

Curr Biol ; 31(19): 4282-4292.e6, 2021 10 11.

Article em En | MEDLINE | ID: mdl-34388373

Assuntos

Proteínas de Caenorhabditis elegans; Caenorhabditis elegans; Animais; Aminas Biogênicas/metabolismo; Caenorhabditis elegans/fisiologia; Proteínas de Caenorhabditis elegans/metabolismo; Canais Iônicos/metabolismo; Receptores de Serotonina/metabolismo

Palavras-chave

C. elegans; behavioural plasticity; dopamine; learning; ligand-gated ion channels; olfaction; serotonin; tyramine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Caenorhabditis elegans / Proteínas de Caenorhabditis elegans Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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