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Telomerase therapy reverses vascular senescence and extends lifespan in progeria mice.
Mojiri, Anahita; Walther, Brandon K; Jiang, Chongming; Matrone, Gianfranco; Holgate, Rhonda; Xu, Qiu; Morales, Elisa; Wang, Guangyu; Gu, Jianhua; Wang, Rongfu; Cooke, John P.
Afiliação
  • Mojiri A; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, 6670 Bertner Ave., R10-South, Houston, TX 77030, USA.
  • Walther BK; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, 6670 Bertner Ave., R10-South, Houston, TX 77030, USA.
  • Jiang C; Department of Biomedical Engineering, Texas A&M University, 101 Bizzell St., College Station, TX 77840, USA.
  • Matrone G; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Holgate R; British Heart Foundation Centre for Cardiovascular Science, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh EH16 4TJ, UK.
  • Xu Q; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, 6670 Bertner Ave., R10-South, Houston, TX 77030, USA.
  • Morales E; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, 6670 Bertner Ave., R10-South, Houston, TX 77030, USA.
  • Wang G; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, 6670 Bertner Ave., R10-South, Houston, TX 77030, USA.
  • Gu J; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, 6670 Bertner Ave., R10-South, Houston, TX 77030, USA.
  • Wang R; Center for Bioinformatics and Computational Biology, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX 77030, USA.
  • Cooke JP; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, 6670 Bertner Ave., R10-South, Houston, TX 77030, USA.
Eur Heart J ; 42(42): 4352-4369, 2021 11 07.
Article em En | MEDLINE | ID: mdl-34389865

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Progéria / Telomerase Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Progéria / Telomerase Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article