Molecular dynamics simulations reveal how H3K56 acetylation impacts nucleosome structure to promote DNA exposure for lesion sensing.

Fu, Iwen; Geacintov, Nicholas E; Broyde, Suse

Fu, Iwen; Geacintov, Nicholas E; Broyde, Suse.

Afiliação

Fu I; Department of Biology, New York University, 100 Washington Square East, New York, NY, 10003, United States. Electronic address: if539@nyu.edu.
Geacintov NE; Department of Chemistry, New York University, 100 Washington Square East, New York, NY, 10003, United States. Electronic address: ng1@nyu.edu.
Broyde S; Department of Biology, New York University, 100 Washington Square East, New York, NY, 10003, United States. Electronic address: broyde@nyu.edu.

DNA Repair (Amst) ; 107: 103201, 2021 11.

Article em En | MEDLINE | ID: mdl-34399316

Assuntos

Nucleossomos

Palavras-chave

DNA unwrapping; DNA- benzo[a]pyrenyl adduct; H3K56 acetylation; Molecular dynamics simulations; Nucleosome core particle; Nucleotide excision repair; Posttranslational modification

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nucleossomos Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nucleossomos Idioma: En Ano de publicação: 2021 Tipo de documento: Article