[Use of fibrinolytics and deoxyribonuclease in patients with pleural infection].
Zhonghua Yi Xue Za Zhi
; 101(30): 2343-2345, 2021 Aug 10.
Article
em Zh
| MEDLINE
| ID: mdl-34404122
ABSTRACT
Just over a decade ago, it was widely accepted that intrapleural instillation of fibrinolytics was ineffective in treatment of pleural infection. Due to the accumulation of clinical study evidence, an expert team from several countries developed an international consensus and recommended that tissue plasminogen activator and deoxyribonuclease should be instilled intrapleurally at the same time as the initial treatment, or as a follow-up treatment after surgery for pleural infection. The recommended dosages are as follows tissue plasminogen activator 10 mg, twice a day, deoxyribonuclease 5 mg, twice a day. The future researches should focus on optimizing the tissue plasminogen activator and deoxyribonuclease schemes and developing more effective fibrinolytics.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Pleurais
/
Derrame Pleural
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2021
Tipo de documento:
Article