Eradication therapy for gastric cancer in Inner Mongolia: A single-center study over 10 years.

ABSTRACT

OBJECTIVE: To understand the characteristics, diagnosis and treatment of gastric cancer in a specific geographical region. METHODS: The retrospective study was conducted at the Affiliated Hospital of Inner Mongolia Medical University, China, and comprised clinical and pathological data of patients with gastric cancer treated from 2007 to 2017. Data was analysed according to the patients' ethnicity, gender, age, tumour location, differentiation degree, Bormann classification, tumour-nodes-metastases staging and pathological type. Statistical analysis was done using SPSS 22. RESULTS: Of the 2,049 patients, 1619(79.01%) were males and 430(20.99%) were females. The overall mean age of the sample was 60.94±10.90 years. The incidence of gastric antrum was the highest, with 830(40.51%) cases. The proportion of gastric cancers was different in different age groups (p=0.001). Of the total, 922(45%) cases were poorly differentiated adenocarcinoma. There were significant differences in the histological types of gastric cancer in different age groups (p=0.001). There were 130(6.3%) cases of Mongolian patients, and the composition ratio of each age group was not significantly different from that of Han ethnicity (p>0.05). However, location was different with 55(42.31%) cases involving oesophago-gastric junction. CONCLUSIONS: The diagnostic rate of gastric cancer in Western Inner Mongolia was relatively low. The incidence of gastric cancer among both Mongolian and Han patients was higher in elderly men. The incidence of gastric antrum was dominant in Han patients, followed by oesophago-gastric junction, while the reverse was true of Mongolian patients.