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Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells.
Okajima, Daisuke; Yasuda, Satoru; Maejima, Takanori; Karibe, Tsuyoshi; Sakurai, Ken; Aida, Tetsuo; Toki, Tadashi; Yamaguchi, Junko; Kitamura, Michiko; Kamei, Reiko; Fujitani, Tomomichi; Honda, Tomoyo; Shibutani, Tomoko; Muramatsu, Sumie; Nakada, Takashi; Goto, Riki; Takahashi, Shu; Yamaguchi, Miki; Hamada, Hirofumi; Noguchi, Yutaka; Murakami, Masato; Abe, Yuki; Agatsuma, Toshinori.
Afiliação
  • Okajima D; Daiichi Sankyo Co., Ltd., Tokyo, Japan. okajima.daisuke.c4@daiichisankyo.co.jp.
  • Yasuda S; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Maejima T; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Karibe T; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Sakurai K; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Aida T; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Toki T; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Yamaguchi J; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Kitamura M; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Kamei R; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Fujitani T; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Honda T; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Shibutani T; Daiichi Sankyo RD Novare Co., Ltd., Tokyo, Japan.
  • Muramatsu S; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Nakada T; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Goto R; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Takahashi S; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Yamaguchi M; Department of Molecular Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
  • Hamada H; Department of Molecular Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
  • Noguchi Y; Department of Molecular Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
  • Murakami M; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Abe Y; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
  • Agatsuma T; Daiichi Sankyo Co., Ltd., Tokyo, Japan.
Mol Cancer Ther ; 20(12): 2329-2340, 2021 12.
Article em En | MEDLINE | ID: mdl-34413126
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Imunoconjugados / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Imunoconjugados / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article