New hPSC SOX9 and INS Reporter Cell Lines Facilitate the Observation and Optimization of Differentiation into Insulin-Producing Cells.

Dettmer, Rabea; Niwolik, Isabell; Mehmeti, Ilir; Jörns, Anne; Naujok, Ortwin

Dettmer, Rabea; Niwolik, Isabell; Mehmeti, Ilir; Jörns, Anne; Naujok, Ortwin.

Afiliação

Dettmer R; Institute of Clinical Biochemistry, Hannover Medical School, 30625, Hannover, Germany.
Niwolik I; Institute of Clinical Biochemistry, Hannover Medical School, 30625, Hannover, Germany.
Mehmeti I; Institute of Clinical Biochemistry, Hannover Medical School, 30625, Hannover, Germany.
Jörns A; Institute of Clinical Biochemistry, Hannover Medical School, 30625, Hannover, Germany.
Naujok O; Institute of Clinical Biochemistry, Hannover Medical School, 30625, Hannover, Germany. naujok.ortwin@mh-hannover.de.

Stem Cell Rev Rep ; 17(6): 2193-2209, 2021 12.

Article em En | MEDLINE | ID: mdl-34415483

Assuntos

Células Secretoras de Insulina; Células-Tronco Pluripotentes; Diferenciação Celular/genética; Linhagem Celular; Humanos; Insulina/metabolismo; Fatores de Transcrição SOX9/genética; Fatores de Transcrição SOX9/metabolismo

Palavras-chave

Human pluripotent stem cells; Insulin; Reporter cells; SOX9; Stem cell-derived beta cells

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes / Células Secretoras de Insulina Tipo de estudo: Guideline Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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