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In vitro and clinical investigations to determine the drug-drug interaction potential of entrectinib, a small molecule inhibitor of neurotrophic tyrosine receptor kinase (NTRK).
Meneses-Lorente, Georgina; Fowler, Stephen; Guerini, Elena; Kowalski, Karey; Chow-Maneval, Edna; Yu, Li; Mercier, Francois; Ullah, Mohammed; Umehara, Kenichi; Brink, Andreas; Buchheit, Vincent; Zwanziger, Elke; Phipps, Alex; Djebli, Nassim.
Afiliação
  • Meneses-Lorente G; Roche Products Ltd, Welwyn Garden City, UK. georgina.meneses-lorente@roche.com.
  • Fowler S; Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Guerini E; Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Kowalski K; Ignyta, Inc, San Diego, CA, USA.
  • Chow-Maneval E; Ignyta, Inc, San Diego, CA, USA.
  • Yu L; Roche Innovation Center, Little Falls, NJ, USA.
  • Mercier F; Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Ullah M; Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Umehara K; Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Brink A; Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Buchheit V; Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Zwanziger E; Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Phipps A; Roche Products Ltd, Welwyn Garden City, UK.
  • Djebli N; Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
Invest New Drugs ; 40(1): 68-80, 2022 02.
Article em En | MEDLINE | ID: mdl-34417912

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzamidas / Receptores Proteína Tirosina Quinases / Indazóis / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzamidas / Receptores Proteína Tirosina Quinases / Indazóis / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2022 Tipo de documento: Article