Montelukast and Coronavirus Disease 2019: A Scoping Review.
Iran J Allergy Asthma Immunol
; 20(4): 384-393, 2021 Aug 07.
Article
em En
| MEDLINE
| ID: mdl-34418892
ABSTRACT
Coronavirus disease 2019 (COVID-19) is an emerging worldwide issue, that has affected a large number of people around the world. So far, many studies have aimed to develop a therapeutic approach against COVID-19. Montelukast (MK) is a safe asthma controller drug, which is considered as a potential antiviral drug for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This review has a systematic approach to investigate the reports on the use of MK as a part of treatment or a prophylactic agent in COVID-19. The search was conducted in PubMed, Web of Science, and Scopus databases and yielded 35 studies containing the influence of MK on SARS-CoV-2. Ultimately, MK appears to be worth being used as an adjuvant therapeutic and prophylactic drug against SARS-CoV-2. Nevertheless, more clinical trials are required to accurately investigate its effectiveness.
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Base de dados:
MEDLINE
Assunto principal:
Quinolinas
/
Sulfetos
/
Antagonistas de Leucotrienos
/
Ciclopropanos
/
Tratamento Farmacológico da COVID-19
/
Acetatos
Tipo de estudo:
Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article