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Elevated Expression of MiR-17 in Microglia of Alzheimer's Disease Patients Abrogates Autophagy-Mediated Amyloid-ß Degradation.
Estfanous, Shady; Daily, Kylene P; Eltobgy, Mostafa; Deems, Nicholas P; Anne, Midhun N K; Krause, Kathrin; Badr, Asmaa; Hamilton, Kaitlin; Carafice, Cierra; Hegazi, Ahmad; Abu Khweek, Arwa; Kelani, Hesham; Nimjee, Shahid; Awad, Hamdy; Zhang, Xiaoli; Cormet-Boyaka, Estelle; Haffez, Hesham; Soror, Sameh; Mikhail, Adel; Nuovo, Gerard; Barrientos, Ruth M; Gavrilin, Mikhail A; Amer, Amal O.
Afiliação
  • Estfanous S; Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Heart and Lung Research Institute, Ohio State University, Columbus, OH, United States.
  • Daily KP; Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
  • Eltobgy M; Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Heart and Lung Research Institute, Ohio State University, Columbus, OH, United States.
  • Deems NP; Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Heart and Lung Research Institute, Ohio State University, Columbus, OH, United States.
  • Anne MNK; Institute for Behavioral Medicine Research, Ohio State University, Columbus, OH, United States.
  • Krause K; Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Heart and Lung Research Institute, Ohio State University, Columbus, OH, United States.
  • Badr A; Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Heart and Lung Research Institute, Ohio State University, Columbus, OH, United States.
  • Hamilton K; Max Planck Unit for the Science of Pathogens, Berlin, Germany.
  • Carafice C; Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Heart and Lung Research Institute, Ohio State University, Columbus, OH, United States.
  • Hegazi A; Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Heart and Lung Research Institute, Ohio State University, Columbus, OH, United States.
  • Abu Khweek A; Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Heart and Lung Research Institute, Ohio State University, Columbus, OH, United States.
  • Kelani H; Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Heart and Lung Research Institute, Ohio State University, Columbus, OH, United States.
  • Nimjee S; Department of Microbial Infection and Immunity, Infectious Diseases Institute, The Heart and Lung Research Institute, Ohio State University, Columbus, OH, United States.
  • Awad H; Department of Biology and Biochemistry, Birzeit University, West Bank, Palestine.
  • Zhang X; Department of Anesthesiology, Wexner Medical Center, The Ohio State University, Columbus, OH, United States.
  • Cormet-Boyaka E; Department of Neurological Surgery, Wexner Medical Center, The Ohio State University, Columbus, OH, United States.
  • Haffez H; Department of Anesthesiology, Wexner Medical Center, The Ohio State University, Columbus, OH, United States.
  • Soror S; Center for Biostatistics, Ohio State University, Columbus, OH, United States.
  • Mikhail A; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, United States.
  • Nuovo G; Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
  • Barrientos RM; Center of Excellence, Helwan Structure Biology Research, Cairo, Egypt.
  • Gavrilin MA; Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
  • Amer AO; Center of Excellence, Helwan Structure Biology Research, Cairo, Egypt.
Front Immunol ; 12: 705581, 2021.
Article em En | MEDLINE | ID: mdl-34426734

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Regulação da Expressão Gênica / Peptídeos beta-Amiloides / Microglia / MicroRNAs / Doença de Alzheimer / Proteólise Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Regulação da Expressão Gênica / Peptídeos beta-Amiloides / Microglia / MicroRNAs / Doença de Alzheimer / Proteólise Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article