LinkedImm: a linked data graph database for integrating immunological data.
BMC Bioinformatics
; 22(Suppl 9): 105, 2021 Aug 25.
Article
em En
| MEDLINE
| ID: mdl-34433410
ABSTRACT
BACKGROUND:
Many systems biology studies leverage the integration of multiple data types (across different data sources) to offer a more comprehensive view of the biological system being studied. While SQL (Structured Query Language) databases are popular in the biomedical domain, NoSQL database technologies have been used as a more relationship-based, flexible and scalable method of data integration.RESULTS:
We have created a graph database integrating data from multiple sources. In addition to using a graph-based query language (Cypher) for data retrieval, we have developed a web-based dashboard that allows users to easily browse and plot data without the need to learn Cypher. We have also implemented a visual graph query interface for users to browse graph data. Finally, we have built a prototype to allow the user to query the graph database in natural language.CONCLUSION:
We have demonstrated the feasibility and flexibility of using a graph database for storing and querying immunological data with complex biological relationships. Querying a graph database through such relationships has the potential to discover novel relationships among heterogeneous biological data and metadata.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Armazenamento e Recuperação da Informação
/
Web Semântica
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article