Phlegmonous gastritis developed during chemotherapy for acute lymphocytic leukemia: A case report.
World J Clin Cases
; 9(22): 6493-6500, 2021 Aug 06.
Article
em En
| MEDLINE
| ID: mdl-34435017
ABSTRACT
BACKGROUND:
Phlegmonous gastritis (PG) is a rare bacterial infectious disease characterized by neutrophil-based purulent inflammation of the gastric wall. The most representative causative bacterium is Streptococcus pyogenes, followed by Staphylococcus, Pneumococcus and Enterococcus. Hepatic portal venous gas (HPVG) is considered a potentially fatal condition and is rarely associated with PG. CASESUMMARY:
The white blood cell count of a 70-year-old woman with acute lymphocytic leukemia in complete remission dropped to 100/µL after consolidation chemotherapy. Her vital signs were consistent with septic shock. Venous blood culture revealed the presence of Bacillus cereus. Abdominal computed tomography (CT) and esophagogastroduodenoscopy (EGD) showed marked thickening of the gastric wall. As with the other findings, CT was suggestive of HPVG, and EGD showed pseudomembrane-like tissue covering the superficial mucosa. Histopathological examination of gastric biopsy specimens showed mostly necrotic tissue with lymphocytes rather than neutrophils. Culture of gastric specimens revealed the presence of Bacillus cereus. We finally diagnosed this case as PG with Bacillus cereus-induced sepsis and HPVG. This patient recovered successfully with conservative treatment, chiefly by using carbapenem antibiotics.CONCLUSION:
The histopathological finding of this gastric biopsy specimen should be called "neutropenic necrotizing gastritis".
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article